What is T-cell transfer therapy and what does it treat?
T-cell transfer therapy is a type of immunotherapy that enhances the ability of T cells, a key part of the immune system, to recognize and destroy cancer cells. This treatment involves collecting T cells from a patient, modifying or expanding them in a laboratory to improve their cancer-fighting capabilities, and then reintroducing them into the patient’s body.
T-cell transfer therapy is primarily used to treat advanced cancers, such as melanoma, lymphoma, and certain leukemias.
How does T-cell transfer therapy work?
In T-cell transfer therapy, T cells are first extracted from the patient’s blood or tumor tissue. The collected T cells are grown in large numbers in a lab and are sometimes genetically modified to better recognize and attack cancer cells. The enhanced T cells are then reintroduced back into the patient via an IV infusion to attach cancer cells more effectively.
What are side effects of T-cell transfer therapy?
The side effects of T-cell transfer therapy can range from mild to severe, depending on the individual and the specific therapy used. Common side effects include:
- Fatigue
- Fever and chills
- Low blood pressure
- Nausea and vomiting
- Cytokine release syndrome, causing flu-like symptoms
- Neurological effects, such as confusion or seizures
Talk with your hematology oncologist to determine whether T-cell transfer therapy is right for you.