Skip to main content
 
 

Vaginal Cancer

 

What is vaginal cancer?

Vaginal cancer is a rare type of cancer that begins in the cells of the vagina, which is the muscular canal that connects the uterus to the external genitals. Vaginal cancer is more commonly diagnosed in women over the age of 60, although it can occur at any age. It is important to note that vaginal cancer is different from cervical cancer, which starts in the cervix.

The majority of vaginal cancers are squamous cell carcinomas, which develop from the squamous cells lining the vagina. Other types include adenocarcinoma (arising from glandular cells) and melanoma (cancer of pigment-producing cells).

What are risk factors for vaginal cancer?

Several factors may increase the risk of developing vaginal cancer. These include:

  • Advanced age
  • Previous history of cervical cancer
  • Human papillomavirus (HPV) infection
  • History of vaginal intraepithelial neoplasia (VAIN) or other precancerous conditions
  • A weakened immune system
  • Smoking
  • Exposure to diethylstilbestrol (DES) in utero (a synthetic estrogen previously prescribed to some pregnant women)
  • Family history of vaginal or cervical cancer.

What are symptoms of vaginal cancer?

The symptoms of vaginal cancer may include:

  • Abnormal vaginal bleeding, such as postmenopausal bleeding
  • Bleeding after sexual intercourse
  • Bleeding between periods
  • Pain during sexual intercourse
  • Vaginal discharge
  • A mass or lump in the vagina
  • Pelvic pain
  • Changes in bowel or bladder habits

It is important to note that these symptoms can also be caused by other conditions, so proper evaluation is necessary.

How is vaginal cancer diagnosed and staged?

If vaginal cancer is suspected, various tests may be conducted for diagnosis. These may include a pelvic examination, colposcopy (examination of the vagina and cervix with a special microscope), biopsy (taking a small tissue sample for examination), imaging tests such as ultrasound, CT scan or MRI, and a thorough evaluation of the lymph nodes to determine if the cancer has spread.

Staging is important to determine the extent of the cancer and guide treatment decisions. Vaginal cancer is typically staged based on the TNM system, which considers the size and depth of the tumor, lymph node involvement, and the presence of distant metastasis. Staging helps determine the appropriate treatment approach.

What are treatment options for vaginal cancer?

Treatment options for vaginal cancer depend on various factors, including the stage and type of cancer, the individual's overall health, and their preferences. The main treatment modalities include surgery, radiation therapy, and chemotherapy. Surgery may involve removal of the cancerous tissue, a portion or the entire vagina, and nearby lymph nodes. Radiation therapy may be used alone or in combination with surgery, while chemotherapy is often used in advanced cases or to target cancer cells that have spread.

What is the prognosis for vaginal cancer?

The prognosis for vaginal cancer depends on several factors, including the stage at diagnosis, the type and grade of the cancer, and the individual's response to treatment. Early-stage vaginal cancers have a better prognosis, while advanced-stage cancers may be more challenging to treat.

If you have concerns about vaginal cancer or any gynecological condition, it is important to consult with a healthcare professional, such as a gynecologist or gynecologic oncologist. They can provide a thorough evaluation, accurate diagnosis, and discuss the most appropriate treatment options based on your specific situation.